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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT3
All Species:
29.7
Human Site:
Y220
Identified Species:
54.44
UniProt:
O60678
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60678
NP_005779.1
531
59903
Y220
Q
E
D
E
D
G
V
Y
F
S
S
Y
G
H
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092890
531
59784
Y220
Q
E
D
E
D
G
V
Y
F
S
S
Y
G
H
Y
Dog
Lupus familis
XP_534089
541
60618
Y230
Q
E
D
E
D
G
V
Y
F
S
S
Y
G
H
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q922H1
532
59884
Y217
Q
E
D
E
D
G
V
Y
F
S
S
Y
G
H
Y
Rat
Rattus norvegicus
O70467
528
59401
Y217
Q
E
D
E
D
G
V
Y
F
S
S
Y
G
H
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505718
571
63850
Y260
Q
E
D
E
D
G
V
Y
F
S
S
Y
G
H
Y
Chicken
Gallus gallus
XP_420907
526
59430
Y215
H
E
D
E
D
G
V
Y
F
S
S
Y
G
H
Y
Frog
Xenopus laevis
Q8AV13
369
42306
R75
E
V
R
T
L
T
Y
R
N
S
M
F
H
N
R
Zebra Danio
Brachydanio rerio
Q5RGQ2
419
48204
R125
E
V
R
T
L
T
Y
R
N
S
M
Y
H
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396035
525
60169
Y216
N
C
N
V
D
K
G
Y
F
N
T
Y
S
H
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192186
519
58632
P210
I
A
S
A
A
D
S
P
S
S
N
S
K
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82210
366
41153
Q72
V
V
R
T
K
S
Y
Q
D
V
I
Y
K
N
K
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
K54
R
N
A
I
I
Q
N
K
D
L
F
K
D
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.1
90.9
N.A.
89.8
89.2
N.A.
78.8
70.8
35.4
35.7
N.A.
N.A.
42.5
N.A.
45
Protein Similarity:
100
N.A.
96.8
95.1
N.A.
93.9
93.9
N.A.
85.9
83.2
49.1
52.3
N.A.
N.A.
62.5
N.A.
63.6
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
93.3
6.6
13.3
N.A.
N.A.
33.3
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
93.3
26.6
26.6
N.A.
N.A.
60
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
31.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
54
0
62
8
0
0
16
0
0
0
8
0
0
% D
% Glu:
16
54
0
54
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
62
0
8
8
0
0
8
% F
% Gly:
0
0
0
0
0
54
8
0
0
0
0
0
54
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
16
62
0
% H
% Ile:
8
0
0
8
8
0
0
0
0
0
8
0
0
0
8
% I
% Lys:
0
0
0
0
8
8
0
8
0
0
0
8
16
8
24
% K
% Leu:
0
0
0
0
16
0
0
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% M
% Asn:
8
8
8
0
0
0
8
0
16
8
8
0
0
24
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
47
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% Q
% Arg:
8
0
24
0
0
0
0
16
0
0
0
0
0
0
8
% R
% Ser:
0
0
8
0
0
8
8
0
8
77
54
8
8
0
0
% S
% Thr:
0
0
0
24
0
16
0
0
0
0
8
0
0
0
0
% T
% Val:
8
24
0
8
0
0
54
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
24
62
0
0
0
77
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _